Bohnen N I, Twijnstra A, Jolles J
Department of Neuropsychology and Psychobiology, University of Limburg, Maastricht, The Netherlands.
Neurology. 1993 Jan;43(1):103-6. doi: 10.1212/wnl.43.1_part_1.103.
Recent evidence suggests that the vasopressin analogue desglycinamide-arginine8-vasopressin (DGAVP) might specifically benefit mild brain trauma patients. We investigated the effect of intranasal DGAVP treatment in 32 patients who had sustained a mild head injury for 3 months in a double-blind, placebo-controlled, matched-pairs study. DGAVP did not have a positive effect on cognitive recovery in this group of mildly affected patients.
最近的证据表明,血管加压素类似物去甘氨酰胺-精氨酸8-血管加压素(DGAVP)可能对轻度脑外伤患者有特别的益处。在一项双盲、安慰剂对照、配对研究中,我们调查了鼻内给予DGAVP治疗对32例轻度头部受伤3个月患者的影响。在这组轻度受影响的患者中,DGAVP对认知恢复没有积极作用。