Jones P B, Owen M J, Lewis S W, Murray R M
Department of Psychological Medicine, King's College Hospital, London, United Kingdom.
Acta Psychiatr Scand. 1993 Jan;87(1):6-12. doi: 10.1111/j.1600-0447.1993.tb03322.x.
The relationship between family history of psychosis and cortical sulcal widening on CT scans was investigated. Forty-two schizophrenic subjects with a positive family history were individually matched to 42 schizophrenics with no documented family history and 42 healthy controls. Abnormally wide sulci, as defined on the basis of the normal control data, were significantly more common in the family history negative group (9/42) than in the family history positive group (1/42) or the controls (2/36). No significant correlation was found between cerebral cortical ratings and ventricular size.
研究了精神病家族史与CT扫描上皮质沟增宽之间的关系。42名有精神病家族史阳性的精神分裂症患者分别与42名无家族史记录的精神分裂症患者以及42名健康对照进行匹配。根据正常对照数据定义，异常增宽的脑沟在家族史阴性组（9/42）中比家族史阳性组（1/42）或对照组（2/36）中更为常见。未发现大脑皮质评分与脑室大小之间存在显著相关性。
