Sharma V K, Kaur S, Radotra B D, Kaur I
Department of Dermatology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Int J Dermatol. 1993 Jan;32(1):27-9. doi: 10.1111/j.1365-4362.1993.tb00957.x.
Involvement of the oral cavity in lepromatous leprosy is well-documented. The tongue may demonstrate multiple nodules, thickening, and scarring.
Ten consecutive untreated patients with lepromatous leprosy with a bacteriologic index of 4+ or more were clinically and histopathologically studied for evidence of tongue involvement.
Three patients showed clinical tongue involvement, as a nodulo-plaque lesion in one patient and fissured tongue (lingua plicata) in two patients. Tongue was clinically normal or showed nonspecific changes in the remaining seven patients. Histologic evidence of tongue involvement by lepromatous process was seen in six patients, including three without clinical involvement.
We conclude from this study that the tongue is as prone to involvement by lepromatous process as buccal and palatal mucosa.
口腔受累于瘤型麻风已有充分记录。舌头可能出现多个结节、增厚及瘢痕形成。
对连续10例未经治疗、细菌学指数为4+或更高的瘤型麻风患者进行临床和组织病理学研究，以寻找舌头受累的证据。
3例患者有临床可见的舌头受累，1例为结节-斑块状病变，2例为沟纹舌（皱襞舌）。其余7例患者的舌头临床检查正常或有非特异性改变。6例患者有组织学证据显示瘤型病变累及舌头，其中3例无临床受累表现。
我们从本研究得出结论，舌头与颊黏膜和腭黏膜一样容易受到瘤型病变的累及。
