Doraiswamy P M, McDonald W M, Patterson L, Husain M M, Figiel G S, Boyko O B, Krishnan K R
Department of Psychiatry, Duke University Medical Center, Durham, NC 27710.
AJNR Am J Neuroradiol. 1993 Jan-Feb;14(1):141-3.
To assess the effects of age and gender on the interuncal distance measured from MR images.
High-field strength MR images (axial) of 75 volunteers, 21-82 years old and free of neurologic disorders, were used to measure the interuncal distance.
The interuncal distance increased with age (r = 0.66, P < .0001). The mean (SD) interuncal distance for all subjects was 21.4 (4) mm with a range of 12 to 29 mm.
The interuncal distance in healthy subjects is unlikely to exceed 30 mm. Our data may be of clinical significance in view of a previous report stating that the interuncal distance may be enlarged in pathologic hippocampal degeneration, such as in patients with Alzheimer disease.
评估年龄和性别对从磁共振成像(MR)测量的大脑脚间距离的影响。
对75名年龄在21至82岁且无神经系统疾病的志愿者的高场强MR图像(轴位)进行大脑脚间距离测量。
大脑脚间距离随年龄增加(r = 0.66,P <.0001)。所有受试者的平均(标准差)大脑脚间距离为21.4(4)mm,范围为12至29 mm。
健康受试者的大脑脚间距离不太可能超过30 mm。鉴于之前有报告称在病理性海马退变(如阿尔茨海默病患者)中大脑脚间距离可能增大,我们的数据可能具有临床意义。