Boevé M H, Vrensen G F, Willekens B L, Stades F C, van der Linde-Sipman J S
Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, University of Utrecht, The Netherlands.
Graefes Arch Clin Exp Ophthalmol. 1993;231(1):29-33. doi: 10.1007/BF01681697.
This study provides scanning electron microscopic observations on the early morphogenesis of persistent hyperplastic tunica vasculosa lentis and primary vitreous (PHTVL/PHPV) in canine fetuses at days 28 35 postcoitum (D28 and D35). From previous studies regarding PHTVL/PHPV it is known that a retrolental plaque of fibrovascular tissue is present in eyes of affected canine fetuses from the D33 stage. The contribution of vitreous cells to the formation of the plaque is supported by the results of this study. The lens capsules at the stages described were not found to contain abnormalities such as transparent (thinner) parts or rents, as have been described for postnatal cases of PHTVL/PHPV. These findings support the hypothesis that the capsular anomalies observed in postnatal patients are secondary entities.
本研究对交配后28天和35天（D28和D35）犬胎儿持续性增生性晶状体血管膜和原始玻璃体（PHTVL/PHPV）的早期形态发生进行了扫描电子显微镜观察。从先前关于PHTVL/PHPV的研究可知，从D33阶段开始，受影响犬胎儿的眼睛中存在纤维血管组织的晶状体后斑块。本研究结果支持了玻璃体细胞对斑块形成的作用。在所描述的阶段，未发现晶状体囊含有如PHTVL/PHPV产后病例中所描述的透明（较薄）部分或破裂等异常情况。这些发现支持了以下假设：在产后患者中观察到的囊膜异常是继发性病变。
