Chan T Y, Tomlinson B, Chan W W, Yeung V T, Tse L K
Department of Clinical Pharmacology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin.
J Trop Med Hyg. 1993 Feb;96(1):62-3.
A case of aconitine poisoning following the ingestion of 'chuanwu', the main root of Aconitum carmichaeli, and 'caowu', the root of Aconitum kusnezoffii is described. A 35-year-old man became unwell about 90 minutes after ingesting these herbs and his symptoms lasted for about two days. In addition to the typical gastrointestinal (nausea and vomiting) and neurological (generalized weakness, numbness and paraesthesia) features of aconitine poisoning, there was evidence of cardiotoxicity (hypotension and ventricular ectopics). Management of such patients should include measures to enhance elimination and close monitoring for cardiotoxicity. Legislation controlling the use of such herbs should be considered.
本文描述了一例因摄入乌头(附子的主根)和草乌(北乌头的根)导致的乌头碱中毒病例。一名35岁男子在摄入这些草药约90分钟后身体不适,症状持续了约两天。除了乌头碱中毒典型的胃肠道症状(恶心和呕吐)和神经系统症状(全身无力、麻木和感觉异常)外,还有心脏毒性的证据(低血压和室性早搏)。对此类患者的治疗应包括促进排泄的措施以及对心脏毒性的密切监测。应考虑制定控制此类草药使用的法规。