Hornbeck C L, Czarny R J
Navy Drug Screening Laboratory, San Diego, CA 92134-6900.
J Anal Toxicol. 1993 Jan-Feb;17(1):23-5. doi: 10.1093/jat/17.1.23.
A limited analysis is presented of data accumulated over about three years for specimens containing either nonracemic L-methamphetamine/L-amphetamine or racemic mixtures of the D and L stereoisomers. 55 data points for both nonracemic L-methamphetamine and racemic mixtures show that it is possible to report a specimen containing L-methamphetamine positive for illegal D-methamphetamine based on current guidelines unless chiral assays are performed on selected methamphetamine positives. Generation of only 45 racemic specimens from chiral analysis of about 5,000 urine methamphetamine positives demonstrates the overwhelming prevalence of nonracemic illegal D-methamphetamine in Southern California.
对含有非外消旋L-甲基苯丙胺/L-苯丙胺或D和L立体异构体的外消旋混合物的样本,给出了约三年积累数据的有限分析。非外消旋L-甲基苯丙胺和外消旋混合物的55个数据点表明,根据现行指南,除非对选定的甲基苯丙胺阳性样本进行手性分析,否则有可能将含有L-甲基苯丙胺的样本报告为非法D-甲基苯丙胺阳性。在约5000份尿液甲基苯丙胺阳性样本的手性分析中仅产生45份外消旋样本,这表明在南加州非法D-甲基苯丙胺的非外消旋形式占绝大多数。