Ohm O J, Faerestrand S, Engedal H, Hegbom F, Stangeland L, Hoff P I
Hjerteavdelingen Haukeland sykehus, Bergen.
Tidsskr Nor Laegeforen. 1993 Jan 20;113(2):182-9.
During the period from November 1989 to January 1992, 17 patients with ventricular tachyarrhythmias received an implantable pacemaker-cardioverter-defibrillator. The material consists of three female and 14 male patients with an age range of 13-66 years, mean 50.8 +/- 16.6 years. 13 patients had coronary artery disease, one cardiomyopathy, one a myocarditis sequela and two primary rhythm disorder. Four patients received epicardial and 13 endocardial electrode systems. The observation period varied from 4-30 months (april 1992), mean 15.2 +/- 8.8 months. 11 out of 17 patients (65%) experienced one or more episodes of tachyarrhythmias which was treated successfully with overdrive pacing (ramp or burst), cardioversion or defibrillation. One patient died of heart failure after an observation period of 13 months. His pacemaker-cardioverter-defibrillator had been activated more than 100 times. Two children, 13 and 15 years, were treated successfully for ventricular fibrillation four and five months after implantation of the device. The actual one year survival is 100%. Assuming that therapy with a device had not taken place, and that the six patients who experienced episodes of ventricular fibrillation died, the hypothetical probability of survival would have been 62.1 +/- 12.3%.
在1989年11月至1992年1月期间,17例室性心律失常患者接受了植入式起搏器 - 心脏复律除颤器治疗。患者材料包括3名女性和14名男性,年龄范围为13 - 66岁,平均年龄50.8±16.6岁。13例患者患有冠状动脉疾病,1例患有心肌病,1例为心肌炎后遗症,2例为原发性心律失常。4例患者接受了心外膜电极系统,13例接受了心内膜电极系统。观察期为4 - 30个月(1992年4月),平均15.2±8.8个月。17例患者中有11例(65%)经历了一次或多次心律失常发作,通过超速起搏(斜坡或猝发)、心脏复律或除颤成功治疗。1例患者在观察13个月后死于心力衰竭。他的起搏器 - 心脏复律除颤器已激活100多次。两名分别为13岁和15岁的儿童在植入该设备后4个月和5个月成功治疗了室颤。实际一年生存率为100%。假设未进行该设备治疗,且6例经历室颤发作的患者死亡,那么假设的生存率为62.1±12.3%。