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[使用植入式心脏复律除颤器进行低能量心脏复律治疗室性心动过速和心室颤动]

[Low energy cardioversion with the implantable cardioversion defibrillator devices for treatment of ventricular tachycardia and ventricular fibrillation].

作者信息

Siebels J, Schneider M A, Kuck K H

机构信息

Abteilung Kardiologie, Universitäts-Krankenhaus Eppendorf.

出版信息

Z Kardiol. 1993 Nov;82(11):683-91.

PMID:8291289
Abstract

Programmable implantable cardioverter-defibrillators (ICD) with low energy capabilities for the treatment of ventricular tachycardia were introduced to increase patients acceptance and lengthen battery life. However, no data about efficacy and safety of low energy cardioversion with subsequent defibrillation in ventricular tachycardia and fibrillation are available. Nineteen of 42 patients with documented or inducible ventricular tachycardia before ICD implantation were studied. In all patients the effectiveness of low-energy cardioversion (< or = 4 joules) with subsequent high-energy defibrillation was evaluated in monomorphic ventricular tachycardia and/or ventricular fibrillation. During predischarge programmed stimulation in 13/19 patients, a total of 32 monomorphic ventricular tachycardias occurred, and in only six patients could ventricular fibrillation be induced. A tachycardia-related efficacy of 69% and patient-related efficacy of 46% of the low-energy cardioversion < or = 4 joules was observed. Ten tachycardias were accelerated to ventricular fibrillation or remained unchanged (n = 2). The second shock (energy > 17 joules) terminated seven arrhythmias, whereas a third (30 joules) shock or an external defibrillation (n = 2) was necessary for termination of the remaining three arrhythmias. After induction of ventricular fibrillation as the primary arrhythmia, the first (low-energy) shock terminated 2/16 episodes, whereas the second (high-energy) shock reverted ventricular fibrillation in 11/16 episodes. In one patient, a second high energy shock and in two patients external defibrillation was necessary for conversion of ventricular fibrillation. In one patient, an increase of the defibrillation threshold induced by amiodarone could be identified.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

为提高患者接受度并延长电池寿命,已引入具有低能量功能的可程控植入式心脏复律除颤器(ICD)用于治疗室性心动过速。然而,目前尚无关于室性心动过速和颤动时低能量心脏复律及随后除颤的疗效和安全性数据。对42例ICD植入术前记录或可诱发室性心动过速的患者中的19例进行了研究。在所有患者中,评估了低能量心脏复律(≤4焦耳)随后高能量除颤在单形性室性心动过速和/或室性颤动中的有效性。在13/19例患者出院前的程控刺激期间,共发生32次单形性室性心动过速,仅6例患者可诱发室性颤动。观察到≤4焦耳的低能量心脏复律的心动过速相关疗效为69%,患者相关疗效为46%。10次心动过速加速为室性颤动或未改变(n = 2)。第二次电击(能量>17焦耳)终止了7次心律失常,而其余3次心律失常的终止需要第三次(30焦耳)电击或体外除颤(n = 2)。在将室性颤动作为主要心律失常诱发后,第一次(低能量)电击终止了2/16次发作,而第二次(高能量)电击使11/16次发作的室性颤动恢复。在1例患者中,需要第二次高能量电击,2例患者需要体外除颤来转换室性颤动。在1例患者中,可确定胺碘酮引起的除颤阈值升高。(摘要截短于250字)

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