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肌肉创伤后的免疫组织化学改变。

Immunohistochemical alterations after muscle trauma.

作者信息

Fechner G, Bajanowski T, Brinkmann B

机构信息

Institut für Rechtsmedizin, Universität Münster, Germany.

出版信息

Int J Legal Med. 1993;105(4):203-7. doi: 10.1007/BF01642794.

DOI:10.1007/BF01642794
PMID:8431399
Abstract

The proteins fibrin, fibrinogen, fibronectin and complement C5b-9 were investigated in mechanically damaged skeletal muscle. An accumulation of fibrin, fibrinogen and fibronectin could be observed immediately after intra-vital trauma in damaged fibre zones, later an accumulation at the torn edges of the fibres. The accumulation of complement C5b-9 began one hour after trauma. After post mortem trauma no positive reactions could be observed for any of the proteins. The degree of expression of these proteins can therefore be used to differentiate between vital and postmortem muscle damage as well as the estimation of wound age in the early antemortem time period.

摘要

对机械损伤的骨骼肌中的纤维蛋白、纤维蛋白原、纤连蛋白和补体C5b - 9进行了研究。在活体创伤后,受损纤维区域立即可以观察到纤维蛋白、纤维蛋白原和纤连蛋白的积聚,随后在纤维的撕裂边缘也出现积聚。补体C5b - 9的积聚在创伤后一小时开始。死后创伤后,未观察到任何一种蛋白质有阳性反应。因此,这些蛋白质的表达程度可用于区分生前和死后肌肉损伤,以及估计生前早期伤口的时间。

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1
Immunohistochemical alterations after muscle trauma.肌肉创伤后的免疫组织化学改变。
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