Moore M H, Wong K S, Proudman T W, David D J
Australian Cranio-Facial Unit, Adelaide Medical Centre for Women and Children.
Br J Plast Surg. 1993 Jan;46(1):39-44. doi: 10.1016/0007-1226(93)90063-h.
Progressive hemifacial atrophy (Romberg's disease) manifests variable involvement of the skin, soft tissue and underlying cranio-facial skeleton. Significant bony deformation has been identified in those patients with early onset disease, the result of factors both intrinsic to the disease process and secondary to the abnormal environment in which the skeleton develops (functional matrix). Treatment demands combined osteotomy and augmentation of the skeleton in concert with conventional approaches to soft tissue correction.
进行性半侧面部萎缩（罗姆伯格病）表现为皮肤、软组织及下方颅面骨骼的不同程度受累。在那些早发型疾病患者中已发现明显的骨质变形，这是疾病过程本身的因素以及骨骼发育所处异常环境（功能基质）的继发因素共同作用的结果。治疗需要结合截骨术和骨骼增大术，并配合传统的软组织矫正方法。
