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制动对横纹肌拉伸特性的影响:一项在大鼠身上的实验研究

Immobilization effect on the tensile properties of striated muscle: an experimental study in the rat.

作者信息

Järvinen M

出版信息

Arch Phys Med Rehabil. 1977 Mar;58(3):123-7.

PMID:843203
Abstract

To investigate the effect of immobilization on the tensile properties of atrophied gastrocnemius muscle, the left hind legs of 40 rats were fixed with padded plaster casts for three weeks. Seven to 42 days after starting the immobilization, load-deformation curves were registered from both gastrocnemius muscles of each rat and several parameters assessed from the curves. The rupture always occurred at the muscle belly. The decrease in breaking strength and energy absorption capacity following immobilization for one week averaged 20% and 34%, respectively, and the values fell further to about 32% and 46% at the end of the immobilization (21 days), when compared to the contralateral control muscles of the same animals. The elastic stiffness of the immobilized muscles was markedly decreased but rose nearly to the level of the controls after removal of the casts. The tensile properties of the previously immobilized muscles had not yet reached the control levels three weeks after removal of the casts.

摘要

为研究固定对萎缩腓肠肌拉伸性能的影响,对40只大鼠的左后肢用带衬垫的石膏固定三周。在开始固定后7至42天,记录每只大鼠双侧腓肠肌的负荷-变形曲线,并从曲线评估几个参数。断裂总是发生在肌腹处。与同一只动物的对侧对照肌肉相比,固定一周后断裂强度和能量吸收能力的下降平均分别为20%和34%,在固定结束时(21天),这些值进一步降至约32%和46%。固定肌肉的弹性刚度明显降低,但去除石膏后几乎升至对照水平。去除石膏三周后,先前固定肌肉的拉伸性能尚未达到对照水平。

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