Marino M T, Asp A A, Budayer A A, Marsden J S, Strewler G J
Department of Pharmacology, Walter Reed Army Institute of Research, Washington, DC.
J Intern Med. 1993 Feb;233(2):205-7. doi: 10.1111/j.1365-2796.1993.tb00675.x.
A patient with mixed squamous/basal cell carcinoma of the skin presented with hypercalcaemia and elevated serum levels of parathyroid hormone-related protein (PTH-rP). The tumour was resected, PTH-rP levels declined and the patient became normocalcaemic. This is the first case to associate squamous cell carcinoma of the skin with hypercalcaemia and significant levels of PTH-rP.
一名患有皮肤鳞状/基底细胞混合癌的患者出现高钙血症,血清甲状旁腺激素相关蛋白(PTH-rP)水平升高。肿瘤切除后,PTH-rP水平下降,患者血钙恢复正常。这是首例将皮肤鳞状细胞癌与高钙血症及显著水平的PTH-rP相关联的病例。