Ostbye T, Rochon J
Department of Epidemiology and Biostatistics, University of Western Ontario, London, Canada.
Med Educ. 1993 Jan;27(1):97-101. doi: 10.1111/j.1365-2923.1993.tb00236.x.
This article discusses a very early clinical trial from the Old Testament. One of Daniel's and his companions' tribulations in Babylonia is explicated within the framework of the modern clinical trial. Even if many, or maybe even most, guidelines for good clinical trial practice are violated (it can even be argued that this is not really a clinical trial), a discussion of this biblico-historical episode in, for example, a problem-based course in (clinical) epidemiology or a course in the critical appraisal of the literature, can be a useful (and possibly entertaining) exercise.
本文讨论了一项来自《旧约》的非常早期的临床试验。但以理和他的同伴在巴比伦所经历的磨难之一，在现代临床试验的框架内得到了解析。即便违反了许多甚至可能是大多数良好临床试验规范的准则（甚至可以说这根本算不上是一项临床试验），在例如（临床）流行病学的问题导向课程或文献批判性评估课程中，对这一圣经历史事件进行讨论，也可能是一次有益的（或许还很有趣）实践。
