[患有特发性呼吸窘迫综合征（IRDS）的新生儿的肾小球滤过率]

[Glomerular filtration rate in newborn infants with idiopathic respiratory insufficieny syndrome (IRDS)].

作者信息

Jasso Gutiérrez L, Falcón Díaz O, Casimiro Pantoja B

出版信息

Bol Med Hosp Infant Mex. 1977 Mar-Apr;34(2):271-81.

Abstract

The speed of glomerular filtration (GFR) was studied in 16 healthy newborns and in 19 with idiopathic respiratory insufficiency syndrome (IRDS). It turned to be 30.22 +/- 10.23 ml/min/1.73 m2 for healthy cases and of 17.49 +/- 9.71 for those with IRDS; significant dirrerence (p less than 0.001). The same situation was true when preterm or healthy full term cases were compared with those with IRDS. No correlation was shown among GFR with the degree of hypoxemia, hypercapnea or acidosis and even if GFR was 13.89 +/- 10.40 ml./min/1.73 m2 in infants with IRDS who died, if compared with 19.32 +/- 9.17 in those who survived, the difference was not significant. At the end, it is concluded that infants with IRDS have decreased GFR, but the constitutents participating in the phenomenon have not been yet identified.

摘要

对16名健康新生儿和19名患有特发性呼吸功能不全综合征（IRDS）的新生儿的肾小球滤过率（GFR）进行了研究。结果显示，健康新生儿的GFR为30.22±10.23ml/min/1.73m²，患有IRDS的新生儿为17.49±9.71ml/min/1.73m²，差异有统计学意义（p＜0.001）。将早产或健康足月儿与患有IRDS的患儿进行比较时，情况相同。GFR与低氧血症、高碳酸血症或酸中毒程度之间未显示出相关性，即使患有IRDS且死亡的婴儿的GFR为13.89±10.40ml/min/1.73m²，而存活婴儿的GFR为19.32±9.17ml/min/1.73m²，两者差异也无统计学意义。最后得出结论，患有IRDS的婴儿GFR降低，但参与该现象的成分尚未确定。