黑人中的色素减退性结节病。8例报告及超微结构观察

Hypopigmented sarcoidosis in the negro. Report of eight cases with ultrastructural observations.

作者信息

Clayton R, Breathnach A, Martin B, Feiwel M

出版信息

Br J Dermatol. 1977 Feb;96(2):119-25.

Abstract

The dermatological aspects of eight negro patients with hypopigmented sarcoid lesions are described. Light microscope histochemical studies in patients did not reveal the mechanism of the hypopigmentation. However, electronmicroscopy of lesions in two patients showed melanocytes undergoing changes resembling those observed in other acquired hypopigmentary conditions. It is suggested that in these disorders, melanocytes react morphologically in a similar non-specific manner, whatever the prime pathological process.

摘要

本文描述了8例患有色素减退性结节病皮损的黑人患者的皮肤学表现。对这些患者进行的光镜组织化学研究未揭示色素减退的机制。然而，对2例患者皮损的电子显微镜检查显示黑素细胞发生的变化类似于在其他获得性色素减退性疾病中观察到的变化。有人提出，在这些疾病中，无论主要病理过程如何，黑素细胞在形态学上都会以类似的非特异性方式做出反应。