Verschoore M, Bouclier M, Czernielewski J, Hensby C
Clinical Research Department, Valbonne, France.
Dermatol Clin. 1993 Jan;11(1):107-15.
The retinoids provide an important new way of treating dermatologic disorders. They have also proved to have a role in the prevention of new lesion formation. New retinoids, of which adapalene is one, have recently been synthesized in order to obtain similar or better efficacy while reducing skin irritation potential. These new molecules are currently under clinical investigation. Preliminary results are encouraging. In the near future, an expanded range of topical retinoids should be available.
维甲酸类药物为治疗皮肤病提供了一种重要的新方法。它们在预防新皮损形成方面也已被证明有一定作用。为了在降低皮肤刺激可能性的同时获得相似或更好的疗效，最近合成了包括阿达帕林在内的新型维甲酸类药物。这些新分子目前正在进行临床研究。初步结果令人鼓舞。在不久的将来，将会有更多种类的外用维甲酸类药物可供使用。
