Castell J A, Castell D O, Schultz A R, Georgeson S
Department of Medicine, Graduate Hospital, Philadelphia, PA 19146.
Dysphagia. 1993;8(1):1-6. doi: 10.1007/BF01351470.
Due to limitations in available technology it has been difficult to obtain data on upper esophageal sphincter (UES) and pharyngeal (P) function under varying physiologic conditions. We used a manometry system with solid-state intraluminal transducers, including a circumferential sphincter transducer, and computer analysis to measure pressure changes in UES and P during wet (5 ml H2O) swallows as the head was moved through a 75 degree arc in nine normal volunteers. UES residual pressure increased markedly and duration of UES relaxation decreased with increasing head extension. Similar decreases were also seen with time between P peak and both UES nadir and UES end. There were no changes in either pharyngeal peak pressures or the duration of the pharyngeal contraction. Head extension produces major changes in UES relaxation and UES/P coordination. These effects may be clinically important when feeding neurologically impaired patients.
由于现有技术的局限性，在不同生理条件下获取食管上括约肌（UES）和咽部（P）功能的数据一直很困难。我们使用了一种带有固态腔内换能器的测压系统，包括一个环形括约肌换能器，并通过计算机分析来测量9名正常志愿者在吞咽5毫升水时，头部在75度弧范围内移动过程中UES和P的压力变化。随着头部伸展增加，UES残余压力显著增加，UES松弛持续时间缩短。在P波峰值与UES最低点和UES结束点之间的时间上也观察到类似的减少。咽部峰值压力和咽部收缩持续时间均无变化。头部伸展导致UES松弛和UES/P协调性发生重大变化。在喂养神经功能受损患者时，这些影响可能具有临床重要性。
