Duckett J W, Lotfi A H
Division of Urology, Children's Hospital of Philadelphia, Pennsylvania.
J Urol. 1993 Mar;149(3):567-9. doi: 10.1016/s0022-5347(17)36150-5.
Bladder reconstruction using bowel segments was advanced when intermittent catheterization proved so acceptable. Access to the reservoir by way of the urethra is often not possible in children, especially boys. Implantation of the isolated appendix into the bladder remnant or colon segment similar to a ureteral reimplant provides a continence mechanism with ready catheter access (the Mitrofanoff principle). Since 1982 we have applied this principle in 41 pediatric cases of bladder reconstruction (64% boys). Primary diagnoses included bladder exstrophy (46%) and myelomeningocele (34%). Extending the concept of a flap valve continence channel with a narrow tube into the reservoir, segments of tapered ileum and ureters were also used (appendix 61%, ileum 12%, ureter 27%). Results of continence (100%) and uncomplicated catheterization (93%) have been satisfactory. Unfortunately, the longer the experience (average 3.2 years of followup), the more stone formation we experienced (32%), which is due to mucus production and bacteriuria as the stone nidus. There were 2 deaths, including 1 from a renal stone obstructing the ureter with sepsis and 1 a likely suicide. Reoperation was required for 3 stomal revisions, 2 bowel obstructions and 7 stone removals in 3 of the 6 cases in which the bladder neck was closed. Unique aspects of these reconstructions are presented, such as our current preference to bury the stoma in the umbilicus (7 cases), placement of the ureteral segment into the perineum as a neourethra and an unusual conjoined twin reconstruction.
当间歇性导尿被证明如此易于接受时,使用肠段进行膀胱重建取得了进展。在儿童中,尤其是男孩,通常无法通过尿道进入储尿囊。将孤立的阑尾植入膀胱残余部分或结肠段,类似于输尿管再植术,可提供一种便于导尿的控尿机制(米特罗法诺夫原理)。自1982年以来,我们已将这一原理应用于41例小儿膀胱重建病例(64%为男孩)。主要诊断包括膀胱外翻(46%)和脊髓脊膜膨出(34%)。通过将带狭窄管的瓣阀控尿通道概念扩展到储尿囊中,还使用了锥形回肠段和输尿管段(阑尾61%,回肠12%,输尿管27%)。控尿结果(100%)和无并发症的导尿情况(93%)令人满意。不幸的是,随着经验的积累(平均随访3.2年),我们经历的结石形成情况越多(32%),这是由于黏液产生和菌尿作为结石病灶所致。有2例死亡,其中1例死于输尿管结石梗阻伴败血症,1例可能为自杀。在6例膀胱颈关闭的病例中,有3例需要再次手术进行3次造口修复、2次肠梗阻治疗和7次结石清除。文中介绍了这些重建手术的独特之处,例如我们目前倾向于将造口埋于脐部(7例)、将输尿管段置于会阴作为新尿道以及一例不寻常的联体双胎重建手术。