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人腮腺唾液对脂肪酸氢过氧化物的还原作用。

Reduction of fatty acid hydroperoxides by human parotid saliva.

作者信息

Terao J, Nagao A, Yuki H, Itoh Y

机构信息

National Food Research Institute, Ministry of Agriculture, Forestry and Fisheries, Ibaraki, Japan.

出版信息

Lipids. 1993 Feb;28(2):121-4. doi: 10.1007/BF02535775.

Abstract

Arachidonic acid hydroperoxide (15-hydroperoxyeicosatetraenoic acid; 15-HPETE) was introduced into human parotid saliva and incubated at 37 degrees C. Straight phase high-performance liquid chromatography analysis of the reaction mixture showed that 15-HPETE was detoxified to its reduced form, 15-hydroxyeicosatetraenoic acid, in the presence of glutathione. Therefore, it is concluded that human parotid saliva possesses fatty acid hydroperoxide-reducing ability. However, its effectiveness was found to be lower than that of blood plasma.

摘要

花生四烯酸氢过氧化物(15-氢过氧化二十碳四烯酸;15-HPETE)被引入人腮腺唾液中,并在37℃下孵育。对反应混合物进行的正相高效液相色谱分析表明,在谷胱甘肽存在的情况下,15-HPETE被解毒为其还原形式15-羟基二十碳四烯酸。因此,可以得出结论,人腮腺唾液具有还原脂肪酸氢过氧化物的能力。然而,发现其效果低于血浆。

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