Kaminaga T, Naitou H, Hamada S, Takamiya M
Biomedical Research Center, University of Osaka School of Medicine.
Nihon Igaku Hoshasen Gakkai Zasshi. 1993 Jan 25;53(1):28-34.
Intramyocardial fatty components are sometimes depicted by CT of the thorax. However, no studies have investigated the distribution, frequency and cause of these components by using statistical analysis. Three hundred forty-five patients with various cardiac diseases were examined with an ultrafast CT scanner, and intramyocardial fatty components were detected in 15 (4.3%) of them. The frequency of intramyocardial fatty components in each disease was as follows: 6% in ischemic heart disease, 7% in Kawasaki disease, 11% in hypertrophic cardiomyopathy (HCM), 18% in dilated cardiomyopathy (DCM) and 33% in arrhythmogenic right ventricular dysplasia (ARVD). Except for patients with HCM, the segments of the ventricles, where the fatty components were detected, agreed well with the segments with asynergy in left ventriculography and/or the segments with perfusion defect in T1 myocardial scintigraphy. Thus, ischemic fatty degeneration was considered to be a main factor in the production of intramyocardial fatty components in these diseases. The focus of arrhythmia was sometimes detected in the segments with intramyocardial fatty components in DCM and ARVD cases. It is suspected that intramyocardial fatty components sometimes produce arrhythmia in these diseases.
胸部CT有时可显示心肌内脂肪成分。然而,尚无研究通过统计分析来调查这些成分的分布、频率及成因。对345例患有各种心脏疾病的患者使用超快速CT扫描仪进行检查,其中15例(4.3%)检测到心肌内脂肪成分。每种疾病中心肌内脂肪成分的频率如下:缺血性心脏病为6%,川崎病为7%,肥厚型心肌病(HCM)为11%,扩张型心肌病(DCM)为18%,致心律失常性右室发育不良(ARVD)为33%。除HCM患者外,检测到脂肪成分的心室节段与左心室造影中无协同运动的节段和/或T1心肌闪烁显像中有灌注缺损的节段高度吻合。因此,缺血性脂肪变性被认为是这些疾病中心肌内脂肪成分产生的主要因素。在DCM和ARVD病例中,有时在有心肌内脂肪成分的节段检测到心律失常的病灶。怀疑心肌内脂肪成分有时会在这些疾病中引发心律失常。