通过黏粒多聚体扩展酵母人工染色体 - Suppr

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超能文献

Extension of yeast artificial chromosomes by cosmid multimers.

作者信息

Davies N P, Brüggemann M

机构信息

AFRC, Institute of Animal Physiology and Genetics Research, Babraham, Cambridge, UK.

出版信息

Nucleic Acids Res. 1993 Feb 11;21(3):767-8. doi: 10.1093/nar/21.3.767.

DOI:10.1093/nar/21.3.767

PMID:8441698

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC309194/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9887/309194/bc9c39e68f4a/nar00052-0393-a.jpg

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Human antibody production in transgenic animals.转基因动物中的人抗体生产。

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本文引用的文献

Cloned human and mouse kappa immunoglobulin constant and J region genes conserve homology in functional segments.克隆的人类和小鼠κ免疫球蛋白恒定区和J区基因在功能片段上保持同源性。

Cell. 1980 Nov;22(1 Pt 1):197-207. doi: 10.1016/0092-8674(80)90168-3.

A small cosmid for efficient cloning of large DNA fragments.一种用于高效克隆大片段DNA的小型黏粒。

Gene. 1980 Nov;11(3-4):291-8. doi: 10.1016/0378-1119(80)90069-4.

A large section of the gene locus encoding human immunoglobulin variable regions of the kappa type is duplicated.编码人κ型免疫球蛋白可变区的基因座的一大段发生了重复。

J Mol Biol. 1985 Jun 5;183(3):291-9. doi: 10.1016/0022-2836(85)90001-4.

Cloning of large segments of exogenous DNA into yeast by means of artificial chromosome vectors.通过人工染色体载体将大片段外源DNA克隆到酵母中。

Science. 1987 May 15;236(4803):806-12. doi: 10.1126/science.3033825.

Meiotic recombination between yeast artificial chromosomes yields a single clone containing the entire BCL2 protooncogene.酵母人工染色体之间的减数分裂重组产生了一个包含整个BCL2原癌基因的单一克隆。

Proc Natl Acad Sci U S A. 1990 Dec;87(24):9913-7. doi: 10.1073/pnas.87.24.9913.

Yeast artificial chromosomes: tools for mapping and analysis of complex genomes.酵母人工染色体：用于复杂基因组图谱绘制与分析的工具。

Trends Genet. 1990 Aug;6(8):248, 255-8. doi: 10.1016/0168-9525(90)90207-m.

Transfer of yeast artificial chromosomes from yeast to mammalian cells.酵母人工染色体从酵母到哺乳动物细胞的转移。

Bioessays. 1991 Oct;13(10):545-50. doi: 10.1002/bies.950131009.

Mitotic recombination of yeast artificial chromosomes.酵母人工染色体的有丝分裂重组

Nucleic Acids Res. 1992 Jun 25;20(12):3135-8. doi: 10.1093/nar/20.12.3135.

Targeted alterations in yeast artificial chromosomes for inter-species gene transfer.

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