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拉各斯大学教学医院的急性肾衰竭:十年回顾

Acute renal failure at the Lagos University Teaching Hospital: a 10-year review.

作者信息

Bamgboye E L, Mabayoje M O, Odutola T A, Mabadeje A F

机构信息

Dialysis Centre, Lagos University Teaching Hospital, University of Lagos, Nigeria.

出版信息

Ren Fail. 1993;15(1):77-80.

PMID:8441842
Abstract

The Dialysis Centre at the Lagos University Teaching Hospital was established in November 1981 as the first unit in West Africa to undertake chronic hemodialysis treatment. More than 500 patients have been managed in the center since then. Of these, 175 were cases of acute renal failure. The causes and outcome of these cases have been reviewed. There were 89 males (50.9%) and 86 females (49.1%). The majority, 111 (63.4%), were aged < 40 years. The main cause was sepsis, which occurred in 67 cases (38.3%). Gynecological and obstetric cases were 45 (25.7%), including 14 cases (8%) of pregnancy toxemia. Other causes were hemorrhage 18 (10.3%), obstructive uropathy 6 (3.4%), acute glomerulonephritis 8 (4.6%), and poisoning with "Holy Water" 6 (3.4%) and other nephrotoxins 9 (5.1%). Sixty-nine patients (39.4%) died in hospital, 92 (52.6%) recovered, and the fate of 14 (8%) was unknown as they were transferred from the hospital. Reasons for the high mortality included delayed hospitalization, selection of severe cases, and inability of patients to afford more than only one session of dialysis even though they needed more. It is hoped that as awareness of the value of dialysis increases and early treatment can be sought, the overall mortality will be reduced.

摘要

拉各斯大学教学医院的透析中心成立于1981年11月,是西非首个开展慢性血液透析治疗的单位。自那时起,该中心已管理了500多名患者。其中,175例为急性肾衰竭病例。对这些病例的病因和治疗结果进行了回顾。男性89例(50.9%),女性86例(49.1%)。大多数患者,111例(63.4%)年龄小于40岁。主要病因是败血症,共67例(38.3%)。妇产科病例45例(25.7%),其中妊娠中毒症14例(8%)。其他病因包括出血18例(10.3%)、梗阻性尿路病6例(3.4%)、急性肾小球肾炎8例(4.6%)、“圣水”中毒6例(3.4%)以及其他肾毒素中毒9例(5.1%)。69例患者(39.4%)在医院死亡,92例(52.6%)康复出院,14例(8%)患者转院后情况不明。高死亡率的原因包括住院延迟、重症病例的选择以及患者即使需要更多透析治疗也无力承担多于一次的透析费用。希望随着对透析价值的认识提高以及能够寻求早期治疗,总体死亡率将会降低。

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