Juva K, Sulkava R, Erkinjuntti T, Valvanne J, Tilvis R
Department of Neurology, University of Helsinki, Finland.
Acta Neurol Scand. 1993 Feb;87(2):106-10. doi: 10.1111/j.1600-0404.1993.tb04086.x.
The Helsinki Aging Study is based on a random sample of 795 subjects aged 75-years (N = 274), 80-years (N = 266) and 85-years (N = 255). A clinical examination including Clinical Dementia Rating (CDR)-scale was carried out in 82% of the cases. 93 demented subjects were found, 17 of whom had mild dementia. The prevalence of moderate and severe dementia was 2.9%, 10.3% and 23.3% in the age groups of 75-year-olds, 80-year-olds and 85-year-olds, respectively. If we take into account also the mild cases, we get the prevalence of dementia 4.6%, 13.1% and 26.7% in the above mentioned age groups, respectively. The proportion of mild dementias was lower than expected, which probably reflects both the difficulties to recognize mild dementia in an elderly population and the relatively small compensatory capacity of elderly people.
赫尔辛基衰老研究基于795名75岁(N = 274)、80岁(N = 266)和85岁(N = 255)受试者的随机样本。82%的病例进行了包括临床痴呆评定量表(CDR)在内的临床检查。发现93名痴呆患者,其中17名患有轻度痴呆。75岁、80岁和85岁年龄组中重度和极重度痴呆的患病率分别为2.9%、10.3%和23.3%。如果我们也将轻度病例考虑在内,上述年龄组中痴呆的患病率分别为4.6%、13.1%和26.7%。轻度痴呆的比例低于预期,这可能既反映了在老年人群中识别轻度痴呆的困难,也反映了老年人相对较小的代偿能力。