Kloess P M, Stulting R D, Waring G O, Wilson L A
Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia.
Am J Ophthalmol. 1993 Mar 15;115(3):309-16. doi: 10.1016/s0002-9394(14)73580-9.
We analyzed 1,010 consecutive penetrating keratoplasties to determine the incidence of postoperative endophthalmitis, the frequency of positive donor rim cultures, and whether a correlation between these two factors exists. There were three cases of bacterial endophthalmitis, all caused by streptococci, and one case of Candida albicans endophthalmitis. In all cases except one case of streptococcal endophthalmitis, the same organism was cultured from the donor rim. We cultured 138 organisms from 128 of 932 donor rims (14%). A remarkable percentage of gram-positive organisms were resistant to gentamicin, the only antibiotic contained in corneal storage media. On the basis of our data and previously published data, we believe that donor material is frequently the source of microorganisms in endophthalmitis after penetrating keratoplasty.
我们分析了1010例连续的穿透性角膜移植术，以确定术后眼内炎的发生率、供体边缘培养阳性的频率，以及这两个因素之间是否存在相关性。有3例细菌性眼内炎，均由链球菌引起，1例白色念珠菌性眼内炎。除1例链球菌性眼内炎外，所有病例的供体边缘培养出的都是同一种微生物。我们从932个供体边缘中的128个（14%）培养出了138种微生物。相当比例的革兰氏阳性菌对角膜保存介质中唯一含有的抗生素庆大霉素耐药。根据我们的数据和先前发表的数据，我们认为供体材料常常是穿透性角膜移植术后眼内炎中微生物的来源。
