Williams S B, Butler B C, Gilkey F W, Kapadia S B, Burton D M
Department of Oral Pathology, Armed Forces Institute of Pathology, Washington, DC 20306.
Arch Pathol Lab Med. 1993 Mar;117(3):315-8.
This article describes histopathologic and immunohistologic features of an epithelioid hemangioendothelioma that presented in the neck of a 40-year-old man. This tumor was unusual because of the presence of osteoclastlike giant cells scattered throughout the entire lesion. The tumor cells reacted positively for factor VIII-related antigen, and the osteoclastlike giant cells were reactive for KP1 antibody, a macrophage-associated antigen. We are aware of only one other previously reported example of soft-tissue epithelioid hemangioendothelioma with an abundance of osteoclast-like giant cells.
本文描述了一名40岁男性颈部出现的上皮样血管内皮瘤的组织病理学和免疫组织学特征。该肿瘤不同寻常之处在于整个病变中散在分布着破骨细胞样巨细胞。肿瘤细胞对VIII因子相关抗原呈阳性反应，破骨细胞样巨细胞对巨噬细胞相关抗原KP1抗体呈阳性反应。据我们所知，之前仅有另外一例软组织上皮样血管内皮瘤含有大量破骨细胞样巨细胞的报道。
