Georgiev S
Vet Med Nauki. 1978;15(4):93-8.
Studied were the agammaglobulinemia and the hypogammaglobulinemia in 120 newborn lambs of which 100 had sucked for the first time at the first hour following birth, 10 had sucked at the ninth hour, and the remaining 10--at the 24th hour. Blood was sampled at the 1st, 2nd, 3rd, 5th, 10th, 24th, and 48th hour, and was immunoelectrophoretically studied after Grabar. Precipitation was done with hyperimmune antiovine gammaglobulin serum. Part of the lambs with agammaglobulinemia were killed and the small intestine was used to prepare extracts for an immunoelectrophoretic study after Grabar and for establishing gammaglobulins. It was found that lambs that had first sucked at the 1st hour following birth the resorption of the colostral gammaglobulin at the various hours later on varied. In the blood serum of 40% of the investigated lambs at the 1st hour there were gammaglobulins; gammaglobulins in 96% of the animals at the 24th hour after they had first sucked. A delayed first sucking after birth--at the 10th and 24th hour--led to hypo- and agammaglobulinemia. In the blood of such lambs at the 48th hour after sucking the gammaglobulins were 0.70 and 0.95 g% less as against the amount of gammaglobulins in lambs that had sucked for the first time at the first hour after birth.
对120只新生羔羊的无丙种球蛋白血症和低丙种球蛋白血症进行了研究，其中100只在出生后的第一小时首次吮乳，10只在第九小时吮乳，其余10只在第24小时吮乳。在第1、2、3、5、10、24和48小时采集血液，并按照格拉巴尔法进行免疫电泳研究。用超免疫抗羊丙种球蛋白血清进行沉淀。处死部分患有无丙种球蛋白血症的羔羊，取小肠制备提取物，用于按照格拉巴尔法进行免疫电泳研究和确定丙种球蛋白。结果发现，出生后第一小时首次吮乳的羔羊，随后不同时间初乳中丙种球蛋白的吸收情况各不相同。在首次吮乳后第1小时，40%被调查羔羊的血清中有丙种球蛋白；在首次吮乳后第24小时，96%的动物体内有丙种球蛋白。出生后首次吮乳延迟至第10小时和第24小时，会导致低丙种球蛋白血症和无丙种球蛋白血症。与出生后第一小时首次吮乳的羔羊相比，此类羔羊在吮乳后第48小时血液中的丙种球蛋白含量分别低0.70和0.95 g%。
