Schubeus P, Schörner W, Sander B, Hansen K, Lanksch W R, Felix R
Strahlenklinik und Poliklinik, Universitätsklinikum Rudolf Virchow, Freie Universität Berlin.
Rofo. 1993 Feb;158(2):154-9. doi: 10.1055/s-2008-1032621.
Aim of this study was to assess the value of Gd-DTPA administration in MRI of cervical disk herniations. In 34 patients, showing 40 cervical disk herniations, plain proton density- and T1-weighted as well as contrast-enhanced T1-weighted 2D-FLASH images were generated. Contrast between the herniated material and the CSF already was sufficient without administration of Gd-DTPA in all cases. Sufficient contrast between the herniations and the intraforaminal structures was obtained in 13/40 cases and 40/40 cases on plain and contrast-enhanced images, respectively. Definition of the herniated disks was judged to be sufficient in 30/40 cases on plain images and 40/40 cases on contrast-enhanced images. The diagnostic value of the images was improved in 3/12 lateral and 7/8 intraforaminal herniations by contrast administration, whereas there was no significant increase in diagnostic value in posterior or posterolateral herniations. As a result, Gd-DTPA administration is recommended if definition of lateral and intraforaminal disk herniations in MRI is poor.
本研究的目的是评估钆喷酸葡胺（Gd-DTPA）在颈椎间盘突出症磁共振成像（MRI）中的应用价值。对34例存在40处颈椎间盘突出的患者，采集了质子密度加权像、T1加权像以及增强T1加权二维快速低角度激发（2D-FLASH）图像。在所有病例中，即便不使用Gd-DTPA，突出物与脑脊液之间的对比度已然充足。在平扫图像和增强图像上，突出物与椎间孔内结构之间的对比度分别在13/40例和40/40例中达到充足。在平扫图像上，40例中有30例对突出椎间盘的显示被判定为充足；在增强图像上，40例均被判定为充足。通过注射造影剂，12例外侧型和8例椎间孔内型突出中分别有3例和7例图像的诊断价值得到提高，而在后侧或后外侧突出中，诊断价值无显著增加。因此，如果MRI对外侧型和椎间孔内型椎间盘突出的显示不佳，建议使用Gd-DTPA。
