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后颅窝脉络丛乳头状瘤治疗中的术前放疗

Preoperative radiotherapy in the management of posterior fossa choroid plexus papillomas.

作者信息

Carrea R, Polak M

出版信息

Childs Brain. 1977;3(1):12-24. doi: 10.1159/000119645.

Abstract

Although primary radical removal is the procedure of choice in the treatment of choroid plexus papillomas, the age of the child, the size and/or location of the tumor and an above average surgical risk can make advisable the use of a first stage shunt operation, with section of the tentorium if there are signs of upwards tentorial herniation. The present two observations clearly demonstrate that radiotherapy shrinks the vascular stroma of these tumors, thus reducing its size and vascularity making possible the postponement of radical surgery and greatly simplifying the final radical removal of the lesion. Preoperative radiotherapy as well as shunt operations and tentorial section can be considered as first stage procedures for the surgical management of choroid plexus neoplasms in certain cases.

摘要

尽管一期根治性切除是脉络丛乳头状瘤治疗的首选方法,但患儿的年龄、肿瘤的大小和/或位置以及高于平均水平的手术风险,可能使得一期分流手术成为明智之选。如果存在小脑幕上疝的迹象,则需切开小脑幕。目前的这两个病例清楚地表明,放疗可使这些肿瘤的血管基质缩小,从而减小其大小并降低血管化程度,使得根治性手术得以推迟,并大大简化了病变的最终根治性切除。在某些情况下,术前放疗以及分流手术和小脑幕切开术可被视为脉络丛肿瘤外科治疗的一期手术。

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