Primrose E D, Savage J M, Boreham C A, Cran G W, Strain J J
Department of Child Health, Queen's University of Belfast.
Ir Med J. 1993 Jan;86(1):17-9.
Although Northern Ireland leads the world in terms of coronary heart disease mortality, the prevalence of coronary risk factors in the childhood population is largely unknown. The aims of the present study were to assess the feasibility of collecting this data and to undertake a preliminary investigation of risk factor status. One hundred and three out of 154 first year pupils (67%), mean age 12.3 years from a Belfast secondary school had their height, weight, pubertal status and blood pressure estimated. Blood samples were analysed for serum cholesterol and thiocyanate in 99 children. 31% had elevated cholesterol, 13% had raised blood pressure, 13% were overweight and 5% were identified as smokers. There appeared to be relatively high risk factor levels with at least one risk factor present in 45% of children. No difficulties arose in compliance with the test protocol suggesting that coronary profiling in children on a large-scale is feasible. On the basis of these results, we feel that coronary risk factor status in Northern Irish children needs further evaluation.
尽管北爱尔兰在冠心病死亡率方面位居世界前列，但儿童群体中冠心病风险因素的流行情况在很大程度上尚不清楚。本研究的目的是评估收集这些数据的可行性，并对风险因素状况进行初步调查。贝尔法斯特一所中学的154名一年级学生（平均年龄12.3岁）中有103名（67%）接受了身高、体重、青春期状态和血压测量。对99名儿童的血液样本进行了血清胆固醇和硫氰酸盐分析。31%的儿童胆固醇升高，13%的儿童血压升高，13%的儿童超重，5%的儿童被认定为吸烟者。似乎风险因素水平相对较高，45%的儿童至少存在一种风险因素。在遵守测试方案方面没有出现困难，这表明对儿童进行大规模的冠心病风险评估是可行的。基于这些结果，我们认为北爱尔兰儿童的冠心病风险因素状况需要进一步评估。
