Stokes M A, Barry K, Sullivan R, Byrne J, Callaghan J, Given H F
Dept of Pathology, University College Hospital, Galway.
Ir Med J. 1993 Jan;86(1):24-6.
In the last 12 years, 72 operations have been performed on 41 patients for Crohn's disease in this hospital. The patients were predominantly young (mean age 32 yrs) and there were more females than males. 28 had ileocolic disease, three small intestinal, two pan-enteric and eight colonic. Pain (in 76%), diarrhoea (56%) and weight loss (66%) were the main presenting symptoms. Diarrhoea occurred in all those with colonic disease, but in only 43% of those with ileocolic disease. A right hemicolectomy (28 patients), colonic resection (12) and small intestinal resection (9) were the commonest operations. There were no deaths. 22 patients had a total of 26 complications after surgery, eight necessitating further surgery. The mean post-operative stay was 15 days, being lowest in those with ileocolic disease. 19 patients have required only one operation, with a mean follow-up of 5.3 years. These patients also had significantly less complications (p < 0.05). Half of the patients requiring surgery for Crohn's disease have done very well. The other half require many operations and have a substantial morbidity.
在过去12年里，本院对41例克罗恩病患者实施了72次手术。患者以年轻人为主（平均年龄32岁），女性多于男性。28例患有回结肠疾病，3例为小肠疾病，2例为全肠道疾病，8例为结肠疾病。主要症状为疼痛（76%）、腹泻（56%）和体重减轻（66%）。所有结肠疾病患者均出现腹泻，但回结肠疾病患者中仅有43%出现腹泻。最常见的手术是右半结肠切除术（28例患者）、结肠切除术（12例）和小肠切除术（9例）。无死亡病例。22例患者术后共出现26次并发症，其中8例需要再次手术。术后平均住院时间为15天，回结肠疾病患者住院时间最短。19例患者仅接受了一次手术，平均随访5.3年。这些患者的并发症也明显较少（p<0.05）。一半因克罗恩病需要手术的患者恢复得很好。另一半则需要多次手术，且发病率较高。
