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生长因子:正常生长与肿瘤生长的调节

Growth factors: regulation of normal and neoplastic growth.

作者信息

Pusztai L, Lewis C E, Lorenzen J, McGee J O

机构信息

University of Oxford, Nuffield Department of Pathology and Bacteriology, John Radcliffe Hospital, U.K.

出版信息

J Pathol. 1993 Feb;169(2):191-201. doi: 10.1002/path.1711690204.

Abstract

This paper presents an overview of current trends in growth factor research. The first part of the review considers the current classification of growth factors and their receptors. A model of cell proliferation regulation by growth factors is then presented. The final section reviews the latest concepts of the involvement of growth factors in the development of neoplasia.

摘要

本文概述了生长因子研究的当前趋势。综述的第一部分考虑了生长因子及其受体的当前分类。然后提出了生长因子调节细胞增殖的模型。最后一部分综述了生长因子在肿瘤形成过程中作用的最新概念。

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