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生长因子:正常生长与肿瘤生长的调节

Growth factors: regulation of normal and neoplastic growth.

作者信息

Pusztai L, Lewis C E, Lorenzen J, McGee J O

机构信息

University of Oxford, Nuffield Department of Pathology and Bacteriology, John Radcliffe Hospital, U.K.

出版信息

J Pathol. 1993 Feb;169(2):191-201. doi: 10.1002/path.1711690204.

DOI:10.1002/path.1711690204
PMID:8445485
Abstract

This paper presents an overview of current trends in growth factor research. The first part of the review considers the current classification of growth factors and their receptors. A model of cell proliferation regulation by growth factors is then presented. The final section reviews the latest concepts of the involvement of growth factors in the development of neoplasia.

摘要

本文概述了生长因子研究的当前趋势。综述的第一部分考虑了生长因子及其受体的当前分类。然后提出了生长因子调节细胞增殖的模型。最后一部分综述了生长因子在肿瘤形成过程中作用的最新概念。

相似文献

1
Growth factors: regulation of normal and neoplastic growth.生长因子:正常生长与肿瘤生长的调节
J Pathol. 1993 Feb;169(2):191-201. doi: 10.1002/path.1711690204.
2
Expression of growth factors, growth-inhibiting factors, and their receptors in invasive breast cancer. II: Correlations with proliferation and angiogenesis.生长因子、生长抑制因子及其受体在浸润性乳腺癌中的表达。II:与增殖和血管生成的相关性。
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[The regulation network of growth factors].
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Growth factors and growth factor receptors.生长因子与生长因子受体。
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Differential regulation of cell proliferation and protease secretion by epidermal growth factor and amphiregulin in tumoral versus normal breast epithelial cells.表皮生长因子和双调蛋白对肿瘤性与正常乳腺上皮细胞中细胞增殖和蛋白酶分泌的差异调节
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TIEG1 inhibits breast cancer invasion and metastasis by inhibition of epidermal growth factor receptor (EGFR) transcription and the EGFR signaling pathway.TIEG1 通过抑制表皮生长因子受体(EGFR)转录和 EGFR 信号通路抑制乳腺癌的侵袭和转移。
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