Pusztai L, Lewis C E, Lorenzen J, McGee J O
University of Oxford, Nuffield Department of Pathology and Bacteriology, John Radcliffe Hospital, U.K.
J Pathol. 1993 Feb;169(2):191-201. doi: 10.1002/path.1711690204.
This paper presents an overview of current trends in growth factor research. The first part of the review considers the current classification of growth factors and their receptors. A model of cell proliferation regulation by growth factors is then presented. The final section reviews the latest concepts of the involvement of growth factors in the development of neoplasia.
本文概述了生长因子研究的当前趋势。综述的第一部分考虑了生长因子及其受体的当前分类。然后提出了生长因子调节细胞增殖的模型。最后一部分综述了生长因子在肿瘤形成过程中作用的最新概念。