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觉醒诱导的自由活动大鼠皮质[K⁺]升高。

Arousal-induced increase of cortical [K+] in unrestrained rats.

作者信息

Korytová H

出版信息

Experientia. 1977 Feb 15;33(2):242-4. doi: 10.1007/BF02124090.

Abstract

Changes of extracellular concentration of brain potassium [K+]e were studied in lightly anesthetized unrestrained rats with ion-selective K+-microelectrodes introduced into the cerebral cortex with a head-mounted microdrive system. Nociceptive stimuli elicited EEG arousal lasting for 47 sec on the averag which was accompained by an increase of [K+]e from 3.0 mM to 3.31 +/- 0.04 mM.

摘要

在轻度麻醉、未受束缚的大鼠中,使用头戴式微驱动系统将离子选择性钾微电极插入大脑皮层,研究脑外钾离子浓度([K⁺]e)的变化。伤害性刺激引起脑电图觉醒,平均持续47秒,同时[K⁺]e从3.0毫摩尔/升增加到3.31±0.04毫摩尔/升。

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