Talafantová M, Kolínská J
Folia Biol (Praha). 1977 Jan;23(1):76-80.
The aerobic uptake and metabolism of D-fructose in the rings of the small intestine of conventional and germ-free piglets during development was studied. No accumulation of fructose in the intracellular water against its concentration gradient was found. In both groups of animals the intracellular concentration of fructose decreases with increasing age, being highest in the newborn intestine and the sharptest decrease being observed on the first two days of post-natal life. Lactic acid was found to be the main metabolic product of fructose; a considerable amount of it was formed also from endogenous sources of the small intestine. In the newborn piglet fructose does not affect the formation of lactic acid, on the first two days after birth this effect of fructose is already apparent and more pronounced in germ-free piglets than in conventional ones. Conventional and germ-free animals differ markedly in endogenous lactic acid production. While in the former with increasing age endogenous lactate formation decreases, in the latter it rises after a sharp drop on the first post-natal day.
研究了常规饲养和无菌饲养仔猪发育过程中小肠肠段对D-果糖的需氧摄取和代谢情况。未发现果糖逆浓度梯度在细胞内液中蓄积。两组动物中，果糖的细胞内浓度均随年龄增长而降低，在新生仔猪小肠中最高，且在出生后前两天下降最为明显。乳酸被发现是果糖的主要代谢产物；相当一部分乳酸也由小肠内源性物质生成。在新生仔猪中，果糖不影响乳酸的生成，出生后前两天，果糖的这种作用已很明显，且在无菌仔猪中比在常规饲养仔猪中更显著。常规饲养和无菌饲养的动物在内源性乳酸生成方面存在显著差异。在前者中，内源性乳酸生成随年龄增长而减少，而在后者中，在出生后第一天急剧下降后又上升。
