Albert D J, Jonik R H, Walsh M L
Psychology Department, University of British Columbia, Vancouver, Canada.
Physiol Behav. 1993 Feb;53(2):379-82. doi: 10.1016/0031-9384(93)90221-z.
Females that had become aggressive as a result of cohabiting with a sterile male were ovariectomized and implanted with empty Silastic tubes. Control groups were either sham ovariectomized or ovariectomized and implanted with Silastic tubes providing replacement levels of estradiol and testosterone. Twenty-seven hours following surgery, all animals were tested for aggressiveness toward an unfamiliar female rat. The aggression of ovariectomized females without hormone replacement declined to a minimal level postoperatively and was significantly lower than that of sham-ovariectomized females or ovariectomized females with estradiol and testosterone replacement. Both sham-ovariectomized females and ovariectomized females given hormone replacement displayed a level of aggression close to that observed preoperatively. The aggression of a female rat cohabiting with a sterile male appears to be highly sensitive to the removal of gonadal hormones. This corresponds with observations made on pregnant females and contrasts with those made on lactating females.
因与不育雄性同居而变得具有攻击性的雌性大鼠接受了卵巢切除术，并植入了空的硅橡胶管。对照组要么接受假卵巢切除术，要么接受卵巢切除术并植入能提供雌二醇和睾酮替代水平的硅橡胶管。手术后27小时，对所有动物针对陌生雌性大鼠的攻击性进行测试。未进行激素替代的卵巢切除雌性大鼠的攻击性在术后降至最低水平，且显著低于假卵巢切除雌性大鼠或接受雌二醇和睾酮替代的卵巢切除雌性大鼠。接受假卵巢切除术的雌性大鼠和接受激素替代的卵巢切除雌性大鼠的攻击性水平均接近术前观察到的水平。与不育雄性同居的雌性大鼠的攻击性似乎对性腺激素的去除高度敏感。这与对怀孕雌性大鼠的观察结果相符，与对哺乳期雌性大鼠的观察结果相反。
