Andersen J, Dahlin J, Bruun E
Kirurgisk gastroenterologisk afdeling D, København Amts Sygehus i Gentofte.
Ugeskr Laeger. 1993 Mar 1;155(9):647-9.
Twenty-seven patients were divided at random into two groups following abscess formation and complete reopening of the abdominal wound in a prospective double blind investigation to study the effect of topical sucralfate on the wound healing rate in secondary abdominal wounds. Fifteen patients were treated with sucralfate powder and 11 patients with placebo while one patient was excluded. The two groups were comparable as regards age, sex and factors predisposing to abscess formation. In the sucralfate group the median healing rate was 2.8 cm2/24 hours as compared with 2.4 cm2/24 hours in the placebo group (p = 0.92, Mann-Whitney test). From this investigation, it is concluded that topical application of sucralfate powder does not appear to increase the rate of healing in secondary abdominal wounds after incision of a wound abscess.
在一项前瞻性双盲研究中，27例患者在腹部伤口形成脓肿且完全重新开放后被随机分为两组，以研究局部使用硫糖铝对二期腹部伤口愈合率的影响。15例患者接受硫糖铝粉治疗，11例患者接受安慰剂治疗，1例患者被排除。两组在年龄、性别和易形成脓肿的因素方面具有可比性。硫糖铝组的中位愈合率为2.8平方厘米/24小时，而安慰剂组为2.4平方厘米/24小时（曼-惠特尼检验，p = 0.92）。从这项研究得出的结论是，在伤口脓肿切开后的二期腹部伤口中，局部应用硫糖铝粉似乎不会提高愈合率。
