Fukazawa K, Sakagami M, Umemoto M, Fujita H, Matsunaga T
Department of Otolaryngology, Kinki Central Hospital, Hyogo, Japan.
Acta Otolaryngol Suppl. 1993;501:72-5. doi: 10.3109/00016489309126219.
Endolymphatic sacs of pigmented guinea pigs were examined by light and electron microscopy. Melanocytes were located not only in the subepithelial connective tissue but also in the intercellular spaces between the epithelial cells. They projected their dendrites into the epithelium extensively. Melanosomes in several stages of maturation and well-developed Golgi apparatus were seen in the cytoplasm of the melanocytes. Melanosomes were also observed in the membrane-bound vacuoles of the epithelial cells. These findings suggest that melanocytes in the endolymphatic sac are highly capable of producing tyrosinase, synthesizing melanin and transferring melanosomes to the epithelial cells, while melanocytes in the other parts of the inner ear do not show signs of melanogenesis under normal conditions.
通过光学显微镜和电子显微镜对有色豚鼠的内淋巴囊进行了检查。黑素细胞不仅位于上皮下结缔组织中，也位于上皮细胞之间的细胞间隙中。它们将树突广泛地伸入上皮。在黑素细胞的细胞质中可见处于几个成熟阶段的黑素体和发育良好的高尔基体。在上皮细胞的膜结合空泡中也观察到了黑素体。这些发现表明，内淋巴囊中的黑素细胞具有高度的酪氨酸酶产生能力、合成黑色素并将黑素体转移到上皮细胞的能力，而内耳其他部位的黑素细胞在正常情况下未表现出黑素生成的迹象。
