儿童期胸腺相关肿瘤及肿瘤样病变，临床进展迅速并导致死亡。
Thymus related tumors and tumor-like lesions in childhood with rapid clinical progression and death.
作者信息
Dehner L P, Martin S A, Sumner H W
出版信息
Hum Pathol. 1977 Jan;8(1):53-66. doi: 10.1016/s0046-8177(77)80065-8.
Tumor and tumor-like lesions of the thymus, excluding Hodgkin and nonHodgkin lymphomas, are among the least frequent mediastinal tumors in childhood. For this reason the diagnosis is often overlooked. The clinical and pathologic features of four thymus related masses, three of which were thymomas and one a thymic cyst, are reported in children between the ages of five and 15 years. The thymic cyst occurred in a child with a five year history of aplastic anemia. A rapid clinical course to death occurred in all four cases. The behavior of these lesions is compared with that described in the literature. The impression exists that thymomas in the pediatric age group are much more aggressive than those in adults. There are also some signifant differences in their histopathologic appearance.
胸腺肿瘤及肿瘤样病变（不包括霍奇金淋巴瘤和非霍奇金淋巴瘤）是儿童期最不常见的纵隔肿瘤之一。因此，其诊断常常被忽视。本文报告了5至15岁儿童中4例与胸腺相关肿物的临床和病理特征，其中3例为胸腺瘤，1例为胸腺囊肿。胸腺囊肿发生于一名有5年再生障碍性贫血病史的儿童。所有4例均呈现迅速的临床病程并导致死亡。本文将这些病变的行为与文献中描述的进行了比较。目前的印象是，儿童年龄组的胸腺瘤比成人的更具侵袭性。它们的组织病理学表现也存在一些显著差异。
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