Chromosomal localization of the human ciliary neurotrophic factor gene (CNTF) to 11q12 by fluorescence in situ hybridization.
作者信息
Giovannini M, Romo A J, Evans G A
机构信息
Molecular Genetics Laboratory, Salk Institute for Biological Studies, San Diego, CA 92138-9216.
出版信息
Cytogenet Cell Genet. 1993;63(1):62-3. doi: 10.1159/000133504.
PMID:8449041
Abstract
The human gene for ciliary neurotrophic factor (CNTF) was previously assigned to chromosome 11 by analysis of a panel of somatic cell hybrids. We isolated cosmid clones containing the CNTF gene from an arrayed-chromosome specific library and used fluorescent in situ hybridization to regionally localize the human CNTF gene on chromosome 11. The gene maps at an FLpter of 0.46, corresponding to a cytogenetic band position of 11q12.2.
摘要
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