Fix A G
Department of Anthropology, University of California, Riverside 92521.
Hum Biol. 1993 Apr;65(2):193-210.
Classical isolation by distance models predict a negative exponential relationship between genetic similarity and geographic distance. Furthermore, under random spatial differentiation all alleles should reflect the same pattern because migration affects all loci identically. The effect of nonrandom composition of migrant groups (kin-structured migration) on these predictions was investigated using computer simulation. Spatial autocorrelation analysis of the simulated gene frequencies showed a decline in similarity with distance in the kin-structured experiments, as predicted by the isolation by distance model. However, the spatial autocorrelations were lower and the variation among correlograms of different alleles was greater than what would be expected under random migration. These findings suggest caution in inferring specific evolutionary conclusions from empirical spatial patterns.
经典的距离隔离模型预测，遗传相似性与地理距离之间存在负指数关系。此外，在随机空间分化的情况下，所有等位基因都应反映相同的模式，因为迁移对所有基因座的影响是相同的。我们使用计算机模拟研究了移民群体的非随机组成（亲属结构迁移）对这些预测的影响。对模拟基因频率的空间自相关分析表明，在亲属结构实验中，相似性随距离下降，这与距离隔离模型的预测一致。然而，空间自相关性较低，不同等位基因的相关图之间的差异大于随机迁移情况下的预期。这些发现表明，从经验性空间模式推断特定进化结论时应谨慎。
