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Effect of antihypertensive drugs on ethanol induced gastric lesions: is there a correlation with mucosal blood flow?

作者信息

Rataboli P V, Diniz D'Souza R S, Dhume V G

机构信息

Department of Pharmacology, Goa Medical College, Tiswadi.

出版信息

Indian J Physiol Pharmacol. 1993 Jan;37(1):88-90.

PMID:8449556
Abstract

We studied the effect of five antihypertensive drugs on ethanol-induced gastric haemorrhagic lesions in rats. While hydralazine aggravates these lesions, nifedipine and propranolol have a protective action. On the other hand, enalapril and prazosin have no effect. Thus the effects of antihypertensive drugs on ethanol-induced lesions do not always correlate with their reported actions on gastric mucosal blood flow.

摘要

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