• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

MsmE,一种参与变形链球菌糖转运的脂蛋白。

MsmE, a lipoprotein involved in sugar transport in Streptococcus mutans.

作者信息

Sutcliffe I C, Tao L, Ferretti J J, Russell R R

机构信息

Department of Oral Biology, Dental School, University of Newcastle Upon Tyne, United Kingdom.

出版信息

J Bacteriol. 1993 Mar;175(6):1853-5. doi: 10.1128/jb.175.6.1853-1855.1993.

DOI:10.1128/jb.175.6.1853-1855.1993
PMID:8449892
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC203995/
Abstract

Metabolic labelling by [14C]palmitic acid showed that growth of Streptococcus mutans LT11 in raffinose, an inducer of the msm operon, resulted in increased production of a 45-kDa lipoprotein corresponding to MsmE, which is believed to be a sugar-binding protein. MsmE was also labelled when an msmE clone was expressed in Escherichia coli. The presence of a lipid anchor on MsmE provides a likely explanation of how the sugar-binding protein component of the msm binding protein-dependent multiple sugar transport system is retained at the cell surface.

摘要

用[14C]棕榈酸进行的代谢标记显示,变形链球菌LT11在棉子糖(msm操纵子的诱导物)中生长,导致产生一种与MsmE相对应的45 kDa脂蛋白,据信它是一种糖结合蛋白。当msmE克隆在大肠杆菌中表达时,MsmE也被标记。MsmE上脂质锚定的存在为msm结合蛋白依赖性多种糖转运系统的糖结合蛋白成分如何保留在细胞表面提供了一个可能的解释。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0eb4/203995/22d5a4bc8468/jbacter00048-0312-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0eb4/203995/cfd66b394651/jbacter00048-0312-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0eb4/203995/3cc4f899d08f/jbacter00048-0312-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0eb4/203995/22d5a4bc8468/jbacter00048-0312-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0eb4/203995/cfd66b394651/jbacter00048-0312-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0eb4/203995/3cc4f899d08f/jbacter00048-0312-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0eb4/203995/22d5a4bc8468/jbacter00048-0312-c.jpg

相似文献

1
MsmE, a lipoprotein involved in sugar transport in Streptococcus mutans.MsmE,一种参与变形链球菌糖转运的脂蛋白。
J Bacteriol. 1993 Mar;175(6):1853-5. doi: 10.1128/jb.175.6.1853-1855.1993.
2
A binding protein-dependent transport system in Streptococcus mutans responsible for multiple sugar metabolism.变形链球菌中一种负责多种糖类代谢的依赖结合蛋白的转运系统。
J Biol Chem. 1992 Mar 5;267(7):4631-7.
3
Role of prolipoprotein diacylglyceryl transferase (Lgt) and lipoprotein-specific signal peptidase II (LspA) in localization and physiological function of lipoprotein MsmE in Streptococcus mutans.原脂蛋白二酰甘油转移酶(Lgt)和脂蛋白特异性信号肽酶II(LspA)在变形链球菌脂蛋白MsmE的定位及生理功能中的作用
Oral Microbiol Immunol. 2008 Dec;23(6):515-9. doi: 10.1111/j.1399-302X.2008.00455.x.
4
Cloning and expression of the multiple sugar metabolism (msm) operon of Streptococcus mutans in heterologous streptococcal hosts.变形链球菌多重糖代谢(msm)操纵子在异源链球菌宿主中的克隆与表达。
Infect Immun. 1993 Mar;61(3):1121-5. doi: 10.1128/iai.61.3.1121-1125.1993.
5
The multiple-sugar metabolism (msm) gene cluster of Streptococcus mutans is transcribed as a single operon.变形链球菌的多种糖代谢(msm)基因簇作为一个单一操纵子进行转录。
FEMS Microbiol Lett. 1996 Jul 1;140(2-3):261-4. doi: 10.1016/0378-1097(96)00191-7.
6
Transport of sugars, including sucrose, by the msm transport system of Streptococcus mutans.变形链球菌的msm转运系统对包括蔗糖在内的糖类的转运
J Dent Res. 1993 Oct;72(10):1386-90. doi: 10.1177/00220345930720100701.
7
Regulation of the multiple sugar metabolism operon in Streptococcus mutans.变形链球菌中多种糖代谢操纵子的调控
Dev Biol Stand. 1995;85:343-50.
8
Two closely related ABC transporters in Streptococcus mutans are involved in disaccharide and/or oligosaccharide uptake.变形链球菌中两个密切相关的ABC转运蛋白参与二糖和/或寡糖的摄取。
J Bacteriol. 2008 Jan;190(1):168-78. doi: 10.1128/JB.01509-07. Epub 2007 Oct 26.
9
Regulation of sugar uptake via the multiple sugar metabolism operon by the phosphoenolpyruvate-dependent sugar phosphotransferase transport system of Streptococcus mutans.变形链球菌磷酸烯醇式丙酮酸依赖性糖磷酸转移酶转运系统对多糖代谢操纵子介导的糖摄取的调控
Dev Biol Stand. 1995;85:351-6.
10
Overlapping substrate specificity for sucrose and maltose of two binding protein-dependent sugar uptake systems in Streptococcus mutans.变形链球菌中两种依赖结合蛋白的糖摄取系统对蔗糖和麦芽糖的重叠底物特异性。
FEMS Microbiol Lett. 2007 Jan;266(2):218-23. doi: 10.1111/j.1574-6968.2006.00522.x.

引用本文的文献

1
Two Permeases Associated with the Multifunctional CtaP Cysteine Transport System in Listeria monocytogenes Play Distinct Roles in Pathogenesis.两种与李斯特菌多功能 CtaP 半胱氨酸转运系统相关的渗透酶在发病机制中发挥不同作用。
Microbiol Spectr. 2023 Jun 15;11(3):e0331722. doi: 10.1128/spectrum.03317-22. Epub 2023 May 18.
2
The iron-regulated staphylococcal lipoproteins.铁调节性葡萄球菌脂蛋白。
Front Cell Infect Microbiol. 2012 Apr 4;2:41. doi: 10.3389/fcimb.2012.00041. eCollection 2012.
3
Listeria monocytogenes CtaP is a multifunctional cysteine transport-associated protein required for bacterial pathogenesis.

本文引用的文献

1
Biology, immunology, and cariogenicity of Streptococcus mutans.变形链球菌的生物学、免疫学及致龋性
Microbiol Rev. 1980 Jun;44(2):331-84. doi: 10.1128/mr.44.2.331-384.1980.
2
Evidence for high affinity binding-protein dependent transport systems in gram-positive bacteria and in Mycoplasma.革兰氏阳性菌和支原体中高亲和力结合蛋白依赖性转运系统的证据。
EMBO J. 1988 Dec 1;7(12):3971-4. doi: 10.1002/j.1460-2075.1988.tb03284.x.
3
The pMTL nic- cloning vectors. I. Improved pUC polylinker regions to facilitate the use of sonicated DNA for nucleotide sequencing.
李斯特菌 CtaP 是一种多功能半胱氨酸转运相关蛋白,是细菌发病机制所必需的。
Mol Microbiol. 2009 Nov;74(4):956-73. doi: 10.1111/j.1365-2958.2009.06910.x. Epub 2009 Oct 8.
4
The sigma(E) cell envelope stress response of Streptomyces coelicolor is influenced by a novel lipoprotein, CseA.天蓝色链霉菌的σ(E)细胞包膜应激反应受一种新型脂蛋白CseA的影响。
J Bacteriol. 2006 Oct;188(20):7222-9. doi: 10.1128/JB.00818-06.
5
Mutation of the maturase lipoprotein attenuates the virulence of Streptococcus equi to a greater extent than does loss of general lipoprotein lipidation.与一般脂蛋白脂化缺失相比,成熟酶脂蛋白的突变能更大程度地减弱马链球菌的毒力。
Infect Immun. 2006 Dec;74(12):6907-19. doi: 10.1128/IAI.01116-06. Epub 2006 Oct 2.
6
A new GntR family transcriptional regulator in streptomyces coelicolor is required for morphogenesis and antibiotic production and controls transcription of an ABC transporter in response to carbon source.天蓝色链霉菌中一种新的GntR家族转录调节因子对形态发生和抗生素产生是必需的,并响应碳源控制一种ABC转运蛋白的转录。
J Bacteriol. 2006 Nov;188(21):7477-87. doi: 10.1128/JB.00898-06. Epub 2006 Aug 25.
7
Purification, crystallization and preliminary X-ray diffraction analysis of RafE, a sugar-binding lipoprotein from Streptococcus pneumoniae.肺炎链球菌糖结合脂蛋白RafE的纯化、结晶及初步X射线衍射分析
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Jul 1;62(Pt 7):676-9. doi: 10.1107/S1744309106021695. Epub 2006 Jun 26.
8
Identification of three new genes involved in morphogenesis and antibiotic production in Streptomyces coelicolor.在天蓝色链霉菌中鉴定出三个参与形态发生和抗生素产生的新基因。
J Bacteriol. 2003 Oct;185(20):6147-57. doi: 10.1128/JB.185.20.6147-6157.2003.
9
Involvement of Lsp, a member of the LraI-lipoprotein family in Streptococcus pyogenes, in eukaryotic cell adhesion and internalization.化脓性链球菌中LraI-脂蛋白家族成员Lsp在真核细胞黏附和内化中的作用。
Infect Immun. 2002 Sep;70(9):4859-69. doi: 10.1128/IAI.70.9.4859-4869.2002.
10
Genetic characterization of a Streptococcus mutans LraI family operon and role in virulence.变形链球菌LraI家族操纵子的遗传特征及其在毒力中的作用。
Infect Immun. 2000 Aug;68(8):4441-51. doi: 10.1128/IAI.68.8.4441-4451.2000.
pMTL 尼克克隆载体。I. 改进的pUC多克隆位点区域,便于使用经超声处理的DNA进行核苷酸测序。
Gene. 1988 Aug 15;68(1):139-49. doi: 10.1016/0378-1119(88)90606-3.
4
The structure of signal peptides from bacterial lipoproteins.细菌脂蛋白信号肽的结构。
Protein Eng. 1989 May;2(7):531-4. doi: 10.1093/protein/2.7.531.
5
Carbohydrate uptake in the oral pathogen Streptococcus mutans: mechanisms and regulation by protein phosphorylation.口腔病原菌变形链球菌中的碳水化合物摄取:蛋白质磷酸化的机制与调控
Biochimie. 1989 Sep-Oct;71(9-10):997-1004. doi: 10.1016/0300-9084(89)90103-x.
6
The ami locus of the gram-positive bacterium Streptococcus pneumoniae is similar to binding protein-dependent transport operons of gram-negative bacteria.革兰氏阳性菌肺炎链球菌的ami基因座类似于革兰氏阴性菌的依赖结合蛋白的转运操纵子。
Mol Microbiol. 1990 Apr;4(4):633-44. doi: 10.1111/j.1365-2958.1990.tb00632.x.
7
Lipoproteins in bacteria.细菌中的脂蛋白。
J Bioenerg Biomembr. 1990 Jun;22(3):451-71. doi: 10.1007/BF00763177.
8
Bacterial periplasmic permeases belong to a family of transport proteins operating from Escherichia coli to human: Traffic ATPases.细菌周质通透酶属于一类从大肠杆菌到人类都存在的转运蛋白家族:转运ATP酶。
FEMS Microbiol Rev. 1990 Aug;6(4):429-46. doi: 10.1111/j.1574-6968.1990.tb04110.x.
9
Evidence that protein antigen b of Mycobacterium tuberculosis is involved in phosphate metabolism.有证据表明结核分枝杆菌的蛋白质抗原b参与磷代谢。
J Gen Microbiol. 1990 Mar;136(3):477-80. doi: 10.1099/00221287-136-3-477.
10
PROSITE: a dictionary of sites and patterns in proteins.PROSITE:蛋白质中的位点与模式字典。
Nucleic Acids Res. 1991 Apr 25;19 Suppl(Suppl):2241-5. doi: 10.1093/nar/19.suppl.2241.