Sarnaik A P, Lieh-Lai M W
Department of Pediatrics, Wayne State University School of Medicine, Detroit, Michigan.
Pediatr Clin North Am. 1993 Apr;40(2):337-54. doi: 10.1016/s0031-3955(16)38515-7.
The initial evaluation, stabilization, and subsequent transport of the neurologically compromised child should take into account the pathophysiologic response of the CNS to a variety of injurious factors. Little can be done to avoid neuronal damage from the primary event. Secondary insults resulting from hypoxemia, ischemia, intracranial hypertension, and fluid shifts can and must be prevented to ensure maximum neuronal salvage, however. Maintenance of an adequate airway, breathing, and circulation assume an immediate and ongoing priority. Neuroresuscitation should be directed toward reversing alterations in cerebral metabolism, autoregulation, brain water, and ICP associated with individual pathologic states.
对于神经功能受损儿童的初始评估、病情稳定及后续转运，应考虑中枢神经系统（CNS）对各种损伤因素的病理生理反应。对于原发事件导致的神经元损伤，所能做的甚少。然而，由低氧血症、缺血、颅内高压及液体转移引起的继发性损伤是可以而且必须预防的，以确保最大程度地挽救神经元。维持充足的气道、呼吸及循环是当下和持续的首要任务。神经复苏应致力于逆转与个体病理状态相关的脑代谢、自动调节、脑含水量及颅内压（ICP）的改变。
