脑膜炎球菌感染的治疗。
Treatment of meningococcal infection.
作者信息
Welch S B, Nadel S
机构信息
Department of Paediatrics, Faculty of Medicine, Imperial College London, St Mary's Hospital, London, UK.
出版信息
Arch Dis Child. 2003 Jul;88(7):608-14. doi: 10.1136/adc.88.7.608.
Abstract
Aggressive early treatment of meningococcal disease can reduce mortality. This relies on prompt recognition and treatment of the complications of septicaemia and meningitis, appropriate ongoing intensive care where necessary, and adequate management of multiple organ failure. Most children with meningococcal disease survive intact, but long term sequelae are increasingly recognised and make follow up essential. New treatments continue to be evaluated, but none has so far proven to be effective in further reducing morbidity or mortality. Simple, timely therapeutic manoeuvres may greatly improve the prospects for survival.
摘要
对脑膜炎球菌病进行积极的早期治疗可降低死亡率。这依赖于对败血症和脑膜炎并发症的及时识别与治疗、必要时适当的持续重症监护以及对多器官功能衰竭的充分管理。大多数患脑膜炎球菌病的儿童可完全康复，但长期后遗症越来越受到关注，因此随访至关重要。新的治疗方法仍在不断评估中，但迄今为止，尚无一种方法被证明能进一步降低发病率或死亡率。简单、及时的治疗措施可能会大大改善生存前景。
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