Black R M, Leiter L A, Anderson G H
Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Canada.
Physiol Behav. 1993 Mar;53(3):459-66. doi: 10.1016/0031-9384(93)90139-7.
Despite some reports that aspartame (APM)-sweetened beverages may increase subjective appetite, previously we demonstrated that drinking 280 ml of an APM-sweetened soft drink (170 mg APM) had no effect on appetite, and 560 ml of the same soft drink (340 mg APM) reduced appetite. The present study examined this appetite reduction to determine its cause. Eighteen normal weight young adult males received five treatments (beverage preloads) at 1100 h in a randomized order, one per week: 280 ml of carbonated mineral water (CMW) (control), 560 ml of CMW, 280 ml of CMW with 340 mg of encapsulated APM, 280 ml of CMW sweetened with 340 mg APM, 560 ml of an APM-sweetened soft drink (340 mg APM). Subjective hunger and food appeal were measured from 0930 a.m. to 1230 h, and food intake from a buffet lunch offered at 1205 h was measured. Treatment had no effect on food intake or macronutrient selection. Both 560 ml of CMW or soft drink suppressed appetite, although 280 ml of APM-sweetened mineral water significantly increased subjective appetite relative to the control. Encapsulated APM had no effect on appetite. Therefore, appetite reduction following consumption of an APM-sweetened drink is likely due to drink volume and not the APM content. In addition, consuming APM-sweetened CMW produces a short-term increase in subjective appetite.
尽管有一些报道称，饮用含阿斯巴甜（APM）的饮料可能会增加主观食欲，但我们之前的研究表明，饮用280毫升含APM的软饮料（170毫克APM）对食欲没有影响，而饮用560毫升相同的软饮料（340毫克APM）会降低食欲。本研究对这种食欲降低现象进行了探究，以确定其原因。18名体重正常的年轻成年男性于上午11点按随机顺序接受了五种处理（饮料预负荷），每周一种：280毫升碳酸矿泉水（CMW）（对照）、560毫升CMW、280毫升含340毫克包封APM的CMW、280毫升含340毫克APM的甜味CMW、560毫升含APM的软饮料（340毫克APM）。从上午9点30分至12点30分测量主观饥饿感和食物吸引力，并测量12点05分提供的自助午餐的食物摄入量。处理对食物摄入量或宏量营养素选择没有影响。560毫升的CMW或软饮料均能抑制食欲，尽管280毫升含APM的矿泉水相对于对照显著增加了主观食欲。包封的APM对食欲没有影响。因此，饮用含APM的饮料后食欲降低可能是由于饮料体积而非APM含量。此外，饮用含APM的CMW会使主观食欲短期内增加。
