Puskás E, Medgyesi G A, Gergely J
Allerg Immunol (Leipz). 1978;24(4):299-304.
Authors studied the occurrence of antibodies agglutinating IgG determinants with Rh positive red blood cells covered with IgG molecules of anti-Rh(D) activity treated with papain, pepsin, and trypsin. The occurrence of Fab antibodies was studied in the sera of newborn and of 1-6 years old healthy children, further on quantitative immunoglobulin assays were performed in these to determine whether homoreactant antibodies influence IgG production. Based on their results authors conclude that homoreactant antibodies do not influence IgG production. Authors assume a role in the IgG catabolism viz., they are involved in the elimination of antigen-antibody complexes.
作者研究了用木瓜蛋白酶、胃蛋白酶和胰蛋白酶处理的具有抗Rh（D）活性的IgG分子覆盖的Rh阳性红细胞凝集IgG决定簇的抗体的出现情况。在新生儿和1 - 6岁健康儿童的血清中研究了Fab抗体的出现情况，此外还对这些血清进行了定量免疫球蛋白测定，以确定自身反应性抗体是否影响IgG的产生。基于他们的结果，作者得出结论，自身反应性抗体不影响IgG的产生。作者推测自身反应性抗体在IgG分解代谢中发挥作用，即它们参与抗原 - 抗体复合物的清除。
