Stenhammar L, Wärngård O, Lewander P, Nordvall M
Department of Paediatrics, Central Hospital, Norrköping, Sweden.
Acta Paediatr. 1993 Jan;82(1):49-51. doi: 10.1111/j.1651-2227.1993.tb12514.x.
Oral alimemazine and cisapride, or diazepam and cisapride, or iv midazolam and metoclopramide were given as premedication for small bowel biopsy to three groups of children from a total population of 185 individuals. The biopsy procedures were performed under intermittent fluoroscopy and times for both were recorded. The median biopsy procedure time was significantly shorter in children given iv midazolam and metoclopramide (6 min) compared to those given oral premedication (10 min) (p < 0.001). The median fluoroscopy time was very short in all groups, ranging between 3 and 6 s. It is concluded that iv premedication is superior to oral premedication for small bowel biopsy in children because more effective sedation is obtained.
将口服阿利马嗪和顺阿曲库铵，或地西泮和顺阿曲库铵，或静脉注射咪达唑仑和甲氧氯普胺作为小肠活检的术前用药，给予了来自185名儿童总群体中的三组儿童。活检程序在间歇性荧光透视下进行，并记录了两者的时间。与接受口服术前用药的儿童（10分钟）相比，接受静脉注射咪达唑仑和甲氧氯普胺的儿童的中位活检程序时间显著更短（6分钟）（p<0.001）。所有组的中位荧光透视时间都非常短，在3至6秒之间。得出的结论是，静脉注射术前用药在儿童小肠活检中优于口服术前用药，因为能获得更有效的镇静效果。
