艾滋病患者鸟分枝杆菌-胞内分枝杆菌感染的胃肠道受累情况

Gastro-intestinal involvement in Mycobacterium avium-intracellulare infection of patients with HIV.

作者信息

Hellyer T J, Brown I N, Taylor M B, Allen B W, Easmon C S

机构信息

Department of Medical Microbiology, St Mary's Hospital Medical School, London, U.K.

出版信息

J Infect. 1993 Jan;26(1):55-66. doi: 10.1016/0163-4453(93)96840-m.

DOI:10.1016/0163-4453(93)96840-m

PMID:8454889

Abstract

In a study of 866 faecal specimens from 437 persons, Mycobacterium avium-intracellulare (MAI) was isolated from 14.8% patients with AIDS and 1.3% patients with symptomatic HIV infection but not from any HIV seronegative or asymptomatic HIV seropositive persons. These data support the hypothesis that the gastro-intestinal tract is the portal of entry for MAI and confirm that MAI infection is a manifestation of late-stage HIV disease. Positive faecal cultures correlated well with disseminated disease. The use of faecal cultures for early diagnosis is therefore recommended.

摘要

在一项对来自437人的866份粪便标本的研究中，从14.8%的艾滋病患者和1.3%有症状的HIV感染患者中分离出鸟分枝杆菌-胞内分枝杆菌（MAI），但未从任何HIV血清阴性或无症状HIV血清阳性者中分离出。这些数据支持胃肠道是MAI的进入门户这一假说，并证实MAI感染是晚期HIV疾病的一种表现。粪便培养阳性与播散性疾病密切相关。因此，建议使用粪便培养进行早期诊断。