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胶质瘤的经硬膜扩展

The transdural extension of gliomas.

作者信息

Pompili A, Calvosa F, Caroli F, Mastrostefano R, Occhipinti E, Raus L, Sciarretta F

机构信息

Division of Neurosurgery, Regina Elena National Cancer Institute, Rome, Italy.

出版信息

J Neurooncol. 1993 Jan;15(1):67-74. doi: 10.1007/BF01050265.

Abstract

The extraneural spreading of gliomas is an infrequent occurrence which is not necessarily related to either tumor histology or site. This paper reports two cases, a glioblastoma and an oligodendroglioma, both presenting extradural diffusion. In the first case, where there was severe intracranial hypertension, the tumor found its way out from the neurocranium, far from the site of the operation, perforating the dura and the bone of the cranial base. In the second case, the operation may have facilitated the extraneural invasion. This unusual behaviour of glial tumors is probably less rare than presumed. It may go unnoticed if the attention is concentrated on the usually severe neurological syndrome which is present in these patients.

摘要

胶质瘤的神经外扩散是一种罕见的现象,不一定与肿瘤组织学或部位相关。本文报告了两例病例,一例胶质母细胞瘤和一例少突胶质细胞瘤,均表现为硬膜外扩散。第一例病例中,存在严重的颅内高压,肿瘤从颅腔穿出,远离手术部位,穿透硬脑膜和颅底骨质。在第二例病例中,手术可能促进了神经外侵犯。胶质肿瘤的这种不寻常行为可能并不像推测的那么罕见。如果注意力集中在这些患者通常存在的严重神经综合征上,可能会被忽视。

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