Gidding S S
Division of Cardiology, Children's Memorial Hospital, Chicago, IL 60614.
Am J Dis Child. 1993 Apr;147(4):386-92. doi: 10.1001/archpedi.1993.02160280036014.
The pediatric approach to the primary prevention of coronary artery disease in adults remains controversial. Measurement and intervention to lower serum cholesterol levels have been advocated recently in a selected group of American children by the Expert Panel on Blood Cholesterol Levels in Children and Adolescents of the National Cholesterol Education Program. This article reviews the clinical and scientific data contributing to the controversy surrounding cholesterol in American children. Arguments in favor of and opposed to an aggressive approach to identifying American children with elevated serum cholesterol levels are presented. The rationale for a selective screening approach is demonstrated.
儿科对成人冠状动脉疾病一级预防的方法仍存在争议。美国国家胆固醇教育计划儿童和青少年血液胆固醇水平专家小组最近主张，对选定的一组美国儿童进行测量并采取干预措施以降低血清胆固醇水平。本文回顾了导致美国儿童胆固醇问题争议的临床和科学数据。文中呈现了支持和反对积极识别血清胆固醇水平升高的美国儿童的观点。还阐述了选择性筛查方法的基本原理。
